生物物理学研究生课程的组织和管理由生物物理学跨部门小组（BIG）负责。该小组由那些研究兴趣全部或部分涉及生物物理学的研究生院成员组成。生物物理学涵盖了从分子结构到人类生物学的生命科学的各个领域，并利用物理学的思想和技术来解决生物学问题。BIG的特定子学科是分子
The Biophysics Interdepartmental Group (BIG) at the University of Guelph offers unique programs of masters and doctoral study that seek to further our understanding of biological processes through the application of the concepts and techniques of the physical sciences. Unlike many biophysics graduate programs across Canada, BIG focuses on basic discovery research in the sciences, rather than medical and clinical applications. Experimental research conducted by students within BIG spans the entire breadth of the life sciences spectrum, including biochemistry, molecular biology, microbiology, and human biology. The BIG program provides graduate students with comprehensive education and research training in the field of Biophysics. The program emphasizes multidisciplinary experimental and computational approaches, in which physical and computational tools are applied to biological problems. Collaborative research between faculty members with complementary research interests is actively encouraged, and several graduate students are co-supervised by two research groups.