The Neurobiology of Disease Research Area benefits from an extremely vibrant and interactive local neuroscience community. During development, billions of neurons are generated, migrate, differentiate, and interconnect to form trillions of synaptic connections that characterize the mammalian brain. Understanding how the brain develops, functions, and responds to disease and injury is considered by many to be the last frontier in modern biomedical sciences.<br><br>Faculty in the Neurobiology of Disease Research Area study a broad spectrum of neuroscience topics ranging from molecular & cellular neurobiology, synaptic physiology to systems and behavioral neuroscience, from neurodevelopmental disorders to psychiatric and neurocognitive disorders, from neurodegenerative disorders to neural regeneration, from neuroimmunology, blood brain barrier, sleep, to neuroendocrinology, from retinal diseases to peripheral neuropathies and pain, from fundamental understanding to developing cutting-edge tools. All have an ultimate goal in common: to better understand and to identify therapeutic strategies for the diseased nervous system.