Loughborough University is a top-ten rated university in England for research intensity (REF, 2014) and an outstanding 66% of the work of Loughborough's academic staff who were eligible to be submitted to the REF was judged as ‘world-leading' or ‘internationally excellent', compared to a national average figure of 43%. In choosing Loughborough for your research, you'll work alongside academics who are leaders in their field. You will benefit from comprehensive support and guidance from our Doctoral College, including tailored careers advice, to help you succeed in your research and future career. Cyclopropane rings are an important ring system in a number of pharmaceutical drugs, natural products and materials. The C-H activation of organic molecules is an important way of introducing groups in an atom efficient way. The project will look at C-H activation of cyclopropane rings to make new carbon-carbon bonds and new carbon-heteroatom bonds. A range of metals and metal/ligand systems will be looked at in order to activate the carbon-hydrogen bond on simple cyclopropanes. A range of drug targets and natural product targets will be addressed using the chemistry developed.