We are in the midst of a genomics revolution with new technologies enabling discoveries in human genetics with unprecedented speed and scope. Faculty in the Department of Genetics and Genome Sciences are working to apply these cutting-edge techniques to identify new genetic causes of disease and better understand how an individual's genetic makeup contributes to their disease susceptibility.<br><br>Studies of both rare and common diseases can lead to new mechanistic understanding of disease pathology, the discovery of gene functions, the improvement of disease prediction modeling, and the identification of new therapeutic targets. In our department, David Buchner identifies new genetic causes of rare pediatric endocrine disorders including infertility, growth, and skeletal disorders. Anthony Wynshaw-Boris and Ashleigh Schaffer study human brain development, with Professor Wynshaw-Boris focused on autism and brain overgrowth and Professor Schaffer focused on rare pediatric neurological disease.