Cellular, Molecular, and Microbial Biology (CMMB) at the University of Montana is one of six graduate programs in the Molecular and Biomedical Sciences. Reflecting the breadth of biology, CMMB houses a vibrant group of faculty working on timely problems, using a variety of approaches and model organisms. While diverse in scope, our members are unified in their focus to understand the organizing principles of biology and engage in innovative research that addresses fundamental processes. These include signal transduction, protein trafficking, immunology, cellular lifespan, and the genetics of behavior, as well as molecular mechanisms of diseases such as cancer, Lyme disease, Rift Valley fever, human cytomegalovirus disease, and Q fever. In addition, research in the CMMB Program is addressing emerging themes in the rapidly growing fields of genome evolution, and RNA structure and function.