杜克大学（Duke）拥有关于成瘾的生物学，社会和情感原因以及相对治疗效果的前沿研究计划。瘾和行为改变中心（CABC）是第一个以大学为基础的成瘾中心，其提供有关成瘾的预防，早期干预和治疗的基础和转化神经生物学研究。杜克大学目前的研究项目集中在青春期，以了解自我调节和药物滥用，酒精和尼古丁成瘾的抗渴望机制，新型烟碱化合物对认知的影响以及社会心理干预措施。
Duke has cutting-edge research programs in the biological, social, and emotional causes of addiction and the comparative efficacy of treatment. The Center on Addiction and Behavior Change (CABC) is the first university-based addiction center to offer basic and translational neurobiological research toward the prevention, early intervention, and treatment of addiction. Current research projects at Duke focus on adolescence, to understand self-regulation and substance abuse, anti-craving mechanisms for alcohol and nicotine addiction, the effects of novel nicotinic compounds on cognition, and psychosocial interventions.