数学是我们周围世界结构的识别和分类，对于知识的所有分支和人类的一切努力至关重要。数学结构的丰富性激发了研究的内在美和描述世界的能力。该系提供各种课程，从高中数学的扩展到数学知识的前沿。该部门将其课程打包为灵活的程序，可以适应许多不同的职业道路。鼓励对数学感兴趣的学生，无论他们喜欢哪个专业，都应在注册之前联系数学系讨论课程选择。学生可能会受益于进阶职位，参加旨在为有动力的学生准备研究生学习而开设的荣誉课程，或获得精算学学位的机会。
The mission of the College of Natural Science closely parallels the mission of the University and represents a commitment to research, education, and service. The College of Natural Science is one of the largest colleges within the University and includes academic programs in Biochemistry and Molecular Biology, Biomedical Laboratory Diagnostics, Chemistry, Computational Mathematics, Science, and Engineering, Earth and Environmental Sciences, Human Biology, Integrative Biology, Mathematics, Microbiology and Molecular Genetics, Neuroscience, Physics and Astronomy, Physiology, Plant Biology, and Statistics and Probability. It also includes the W. K. Kellogg Biological Station, a world-class biological research center. All departments within the College offer both undergraduate and graduate students experience conducting research. Students in the College of Natural Science have access to the broad range of research and laboratory facilities on campus, in addition to unique research opportunities in facilities like the MSU/DOE Plant Research Laboratory, the Facility for Rare Isotope Beams, and the W. K. Kellogg Biological Station. Graduate students may also choose to enter one of the college's interdisciplinary research programs in Genetics and Genome Sciences, Cell and Molecular Biology, Mathematics Education, Molecular Plant Science, Neuroscience, and Ecology, Evolution and Behavior.