Carbon nanotube based transdermal drug delivery systems. Comprehensive two-dimensional gas chromatography – development and applications. Development and applications of Solid-Phase Micro-Extraction (SPME) technology for in-vitro and in-vivo analysis. Clinical and pharmaceutical applications of SPME. Non-lethal in-vivo SPME monitoring of biologically significant compounds and environmental contaminants in live tissues. Advances in multidimensional chromatography. Advanced separations techniques in the analysis of environmental pollutants. Passive air sampling in environmental analysis. DNA-aptamer based biosensors for detection in biological fluids. Electroanalytical chemistry, bioanalytical chemistry and in vitro toxicology assays. Micro- and nano-samples by Inductively Coupled Plasma (ICP) atomic emission and ICP-Mass Spectrometry (ICP-MS). Green chromatography. Battery-operated micro-plasmas on-chips. Direct coupling of SPME to Mass Spectrometry (MS) for rapid complex sample determinations. Development of new formats of extraction phases and devices. Investigation of fundamental process in extraction.