The Department of Molecular Biosciences and Bioengineering (MBBE) was established in 1999 as result of a reorganization of the College of Tropical Agriculture and Human Resources (CTAHR). Most faculty in MBBE came from three former CTAHR departments, Plant Molecular Physiology (PMP), Environmental Biochemistry, and Biosystems Engineering. Among them, only PMP had a graduate program that offered both PhD and MS degrees. The PMP Graduate Program started in 1985 and emphasized plant biology and biotechnology.<br><br>After the MBBE department was established, the PMP Graduate Program was reorganized, expanded and renamed as the Graduate Program in MBBE in 2000. The program's scope was widened to include molecular biology, biochemistry, bioinformatics, cell biology, biotechnology, and engineering aspects of plant science, tropical agriculture, aquaculture, environmental bioremediation, bioprocessing, and biomedical sciences.<br><br>With this programmatic expansion, faculty and scientists from other UHM departments and scientific institutes in Hawaii were welcomed into the Program as co-operating and affiliate graduate faculty. The number of students also increased. Guidelines and requirements were developed to maintain high academic standards. These guidelines are reviewed regularly to ensure relevance and contemporariness of the various curricula and fields of study. Currently, many MBBE graduate students are supervised by faculty from John A. Burns School of Medicine, Cancer Research Center, Pacific Biomedical Research Center, Queens Medical Center, Hawaii Agricultural Research Center, Sea Grant College Program, School of Ocean and Earth Science and Technology, College of Engineering and several departments including Microbiology, Zoology, Human Nutrition, Food and Animal Sciences, and Plant and Environmental Protection Sciences. Thus, MBBE became an interdisciplinary graduate program centered around the molecular biosciences but including tropical agriculture, biological and biomedical sciences, and engineering.