化学和生物分子工程学部要求入学的申请人具有满足ABET要求的化学工程或相关领域的学士学位。在居住的前两个学期中，获得化学工程学位的学生将参加在化学工程学的主要领域分配的课程，2个学时的研究生研讨会以及额外的论文研究时间。在第一年末，学生将根据论文研究结果提供书面和口头报告。这些报告以及课程工作表现和助教职责构成了综合评估，使学生能够继续朝着学生的学位目标努力。
Graduate students in Notre Dame's highly ranked Chemical and Biomolecular Engineering department learn from more than 17 faculty members, all of whom are nationally and internationally recognized scholars. Faculty research interests are diverse and include the broad areas of bioengineering, energy and sustainability, theory and simulation, micro- and nanofluidics, and materials and nanotechnology.