五年制课程旨在为那些决定相对较早决定的学生设计，从而获得化学工程，土木工程，电气工程，机械工程，核科学与工程或物理的联合理学学士学位和核科学与工程的理学硕士学位。在他们的大学生涯中，他们希望获得核科学和工程学的学位。学生必须在大二的第二学期提交该计划的申请，并被判定满足该部门的研究生入学要求。
The five-year programs leading to a joint Bachelor of Science in Chemical Engineering, Civil Engineering, Electrical Engineering, Mechanical Engineering, Nuclear Science and Engineering, or Physics and a Master of Science in Nuclear Science and Engineering are designed for students who decide relatively early in their undergraduate career that they wish to pursue a graduate degree in nuclear science and engineering. Students must submit their application for this program during the second term of their junior year and be judged to satisfy the graduate admission requirements of the department. The normal expectations of MIT undergraduates for admission to the five-year program are an overall MIT grade point average (GPA) of at least 4.3, and a strong mathematics, science, and engineering background with a GPA in these subjects of at least 4.0.